When I approached Jusko for interview earlier this year, I told him that the advanced PK/PD book that I plan to write will be a course note style, and I anticipated that the readership of this book would be low. 

My guess was wrong. Since the book was released in early May this year, I have sold 102 copies at Amazon. 102 copies, so 102 readers, way more than I originally thought. For those of you who have purchased this book, thank you for your trust, and I hope you find this book useful. 

This book was self-published as paperback via Amazon’s print on demand (POD), a route that is significantly different from traditional publishing through those big publishers (e.g., Wiley). I would like to be transparent on the book price and my royalty:
◆Book list price: $86.5
◆Amazon commission fee: $34.6 (i.e., 40% of the listed price)
◆Printing cost: $32.04 (printed by Amazon, I chose to use expensive paper with premier color printing)
◆My royalty: $19.86  (i.e., $86.5 - $34.6 - $32.04)   (my royalty was $20.18 initially, and dropped to <$20 after I added one more page (P369) during book update)

I understand that the price of $86.5 is expensive for a textbook. I just want to let you know that I have tried my best to set up a reasonable price, and I did not leave a large royalty for myself. 

This Advanced PK/PD book is extremely valuable, and there is no similar book on the market. If you want to be an expert in PK/PD modeling, this book is worth every penny for you. I am not bragging about myself, I am bragging about this book, as behind this book is Buffalo’s legacy (accumulated over > 60 years). 

This book is the result of a teacher’s love (I wrote it for my own graduate students). As I firmly believe it is a valuable book, naturally I would hope that it can reach more readers. So, I am self-promoting this book, with the goal of more students in our field getting benefit from it. A by-product, not the goal/purpose, is that I will get royalty for the copies sold. 

Self-publishing is fundamentally different from traditional publishing, and my goal is never to make money. I have no plans to use their traditional promoting strategy (free copies or big discount, etc) to advertise my book or lure readers. So, I have to say no to requests for free copies. Thank you for your understanding. 

[Note: Amazon occasionally offers discount (in a random manner) without notifying authors about when and how long is the discount. That is out of my control; and I get same royalty. ]